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Published, Version of Record (VoR) access removed by US government, 1 Dec 2025 Restricted CC BY-NC V4.0
Journal article
Associations of Urban Environment Features with Hypertension and Blood Pressure across 230 Latin American Cities
Environmental health perspectives, v 130(2), pp 27010-27010
Feb 2022
PMID: 35167325
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Features of the urban physical environment may be linked to the development of high blood pressure, a leading risk factor for global burden of disease.
We examined associations of urban physical environment features with hypertension and blood pressure measures in adults across 230 Latin American cities.
In this cross-sectional study we used health, social, and built environment data from the SALud URBana en América Latina (SALURBAL) project. The individual-level outcomes were hypertension and levels of systolic and diastolic blood pressure. The exposures were city and subcity built environment features, mass transit infrastructure, and green space. Odds ratios (ORs) and mean differences and 95% confidence intervals (CIs) were estimated using multilevel logistic and linear regression models, with single- and multiple-exposure models adjusted for individual-level age, sex, education, and subcity educational attainment.
A total of 109,176 participants from 230 cities and eight countries were included in the hypertension analyses and 50,228 participants from 194 cities and seven countries were included in the blood pressure measures analyses. Participants were 18-97 years of age. In multiple-exposure models, higher city fragmentation was associated with higher odds of having hypertension (
; 95% CI: 1.01, 1.21); presence (vs. no presence) of mass transit in the city was associated with higher odds of having hypertension (
; 95% CI: 1.09, 1.54); higher subcity population density was associated with lower odds of having hypertension (
; 95% CI: 0.85, 0.94); and higher subcity intersection density was associated with higher odds of having hypertension [
; 95% CI: 1.04, 1.15). The presence of mass transit was also associated with slightly higher systolic and diastolic blood pressure in multiple-exposure models adjusted for treatment. Except for the association between intersection density and hypertension, associations were attenuated after adjustment for country. An inverse association of greenness with continuous blood pressure emerged after country adjustment.
Our results suggest that urban physical environment features-such as fragmentation, mass transit, population density, and intersection density-may be related to hypertension in Latin American cities. Reducing chronic disease risks in the growing urban areas of Latin America may require attention to integrated management of urban design and transport planning. https://doi.org/10.1289/EHP7870.
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Details
- Title
- Associations of Urban Environment Features with Hypertension and Blood Pressure across 230 Latin American Cities
- Creators
- Ione Avila-Palencia - Drexel UniversityDaniel A Rodríguez - University of California, BerkeleyJ Jaime Miranda - Cayetano Heredia UniversityKari Moore - Drexel UniversityNelson Gouveia - Universidade de São PauloMika R Moran - University of California, BerkeleyWaleska T Caiaffa - Universidade Federal de Minas GeraisAna V Diez Roux - Urban Health Collaborative, Dornsife School of Public Health, Drexel University, Philadelphia, Pennsylvania, USA
- Publication Details
- Environmental health perspectives, v 130(2), pp 27010-27010
- Grant note
- 205177/Z/16/Z / Wellcome Trust Wellcome Trust
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000766770500023
- Scopus ID
- 2-s2.0-85124680249
- Other Identifier
- 991019169686204721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health
- Toxicology