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Associations of Work Hours, Job Strain, and Occupation With Endothelial Function The Multi-Ethnic Study of Atherosclerosis (MESA)
Journal article   Open access   Peer reviewed

Associations of Work Hours, Job Strain, and Occupation With Endothelial Function The Multi-Ethnic Study of Atherosclerosis (MESA)

Luenda E. Charles, Desta Fekedulegn, Paul Landsbergis, Cecil M. Burchfiel, Sherry Baron, Joel D. Kaufman, Karen Hinckley Stukovsky, Kaori Fujishiro, Capri G. Foy, Michael E. Andrew, …
Journal of occupational and environmental medicine, v 56(11), pp 1153-1160
01 Nov 2014
PMID: 25376409
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://europepmc.org/articles/pmc4225634View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Life Sciences & Biomedicine Public, Environmental & Occupational Health Science & Technology
Objective: To investigate associations of work hours, job control, job demands, job strain, and occupational category with brachial artery flow-mediated dilation (FMD) in 1499 Multi-Ethnic Study of Atherosclerosis participants. Methods: Flow-mediated dilation was obtained using high-resolution ultrasound. Mean values of FMD were examined across categories of occupation, work hours, and the other exposures using regression analyses. Results: Occupational category was significantly associated with FMD overall, with blue-collar workers showing the lowest mean values-management/professional = 4.97 +/- 0.22%; sales/office = 5.19 +/- 0.28%; services = 4.73 +/- 0.29%; and blue-collar workers = 4.01 +/- 0.26% (adjusted P < 0.001). There was evidence of effect modification by sex (interaction P = 0.031)-significant associations were observed among women (adjusted P = 0.002) and nearly significant results among men (adjusted P = 0.087). Other exposures were not significantly associated with FMD. Conclusions: Differences in endothelial function may account for some of the variation in cardiovascular disease across occupational groups.

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Collaboration types
Domestic collaboration
Web of Science research areas
Public, Environmental & Occupational Health
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