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Associations of occupation, job control and job demands with intima-media thickness: The Multi-Ethnic Study of Atherosclerosis (MESA)
Journal article   Open access   Peer reviewed

Associations of occupation, job control and job demands with intima-media thickness: The Multi-Ethnic Study of Atherosclerosis (MESA)

Kaori Fujishiro, Ana V Diez Roux, Paul Landsbergis, Sherry Baron, R Graham Barr, Joel D Kaufman, Joseph F Polak and Karen Hinckley Stukovsky
Occupational and environmental medicine (London, England), v 68(5), pp 319-326
May 2011
PMID: 20935285
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://europepmc.org/articles/pmc3073024View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

ObjectivesOccupation has been linked to cardiovascular disease (CVD) incidence and mortality, but few studies have investigated occupation in relation to early atherosclerotic disease. This study examined associations between various occupational characteristics and carotid artery intima-media thickness (IMT) in a multi-ethnic sample.MethodsThe Multi-Ethnic Study of Atherosclerosis (MESA) recruited 6814 adults aged 45–84 years and free of clinical CVD (response rate 60%, 51% female). Questionnaire data were used to determine occupational group (managerial/professional, sales/office, service, blue-collar), psychosocial job characteristics (ie, job demands, job control) and other sociodemographic information.ResultsCommon carotid artery (CCA)-IMT was greater for blue-collar jobs than for management/professional jobs (mean difference=0.012 mm, p=0.049) after adjustment for age, sex, race, place of birth (US or foreign born) and CVD risk factors. Compared to management/professional jobs, internal carotid artery (ICA)-IMT was greater for sales/office, service and blue-collar jobs (mean difference=0.071 mm, p<0.001; 0.057 mm, p=0.009; and 0.110 mm, p<0.001, respectively) after adjustment for age, sex, race and place of birth. The difference between blue-collar jobs and management/professional jobs remained significant after additional adjustment for CVD risk factors, income and education (mean difference=0.048 mm, p=0.045). Higher levels of control at work were associated with thinner CCA-IMT (mean difference=−0.009 mm, p=0.016, adjusted for age, sex, race and place of birth) but not with ICA-IMT. Job demands had no significant association with IMT.ConclusionsBlue-collar jobs and low levels of job control were associated with the development of subclinical atherosclerosis.

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Collaboration types
Domestic collaboration
Web of Science research areas
Public, Environmental & Occupational Health
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