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Asymmetric synthesis of α-hydroxy carboxylic acids: direct oxidation of chiral amide enolates using 2-sulfonyloxaziridines
Journal article   Peer reviewed

Asymmetric synthesis of α-hydroxy carboxylic acids: direct oxidation of chiral amide enolates using 2-sulfonyloxaziridines

Franklin A. Davis and Lal C. Vishwakarma
Tetrahedron letters, v 26(30), pp 3539-3542
1985

Abstract

The direct oxidation of chiral amide enolates to optically active mandelic acid using 2-sulfonyloxaziridine 1 is described. The diastereoselectivity is counterion dependent.

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51 citations in Scopus

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Web of Science research areas
Chemistry, Organic
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