Journal article
Atrial arrhythmias and patient-reported outcomes in adults with congenital heart disease: An international study
Heart rhythm, v 18(5), pp 793-800
01 May 2021
PMID: 32961334
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Atrial arrhythmias (ie, intra-atrial reentrant tachycardia and atrial fibrillation) are a leading cause of morbidity and hospitalization in adults with congenital heart disease (CHD). Little is known about their effect on quality of life and other patient-reported outcomes (PROs) in adults with CHD.
The purpose of this study was to assess the impact of atrial arrhythmias on PROs in adults with CHD and explore geographic variations.
Associations between atrial arrhythmias and PROs were assessed in a cross-sectional study of adults with CHD from 15 countries spanning 5 continents. A propensity-based matching weight analysis was performed to compare quality of life, perceived health status, psychological distress, sense of coherence, and illness perception in patients with and those without atrial arrhythmias.
A total of 4028 adults with CHD were enrolled, 707 (17.6%) of whom had atrial arrhythmias. After applying matching weights, patients with and those without atrial arrhythmias were comparable with regard to age (mean 40.1 vs 40.2 years), demographic variables (52.5% vs 52.2% women), and complexity of CHD (15.9% simple, 44.8% moderate, and 39.2% complex in both groups). Patients with atrial arrhythmias had significantly worse PRO scores with respect to quality of life, perceived health status, psychological distress (ie, depression), and illness perception. A summary score that combines all PRO measures was significantly lower in patients with atrial arrhythmias (–3.3%; P = .0006). Differences in PROs were consistent across geographic regions.
Atrial arrhythmias in adults with CHD are associated with an adverse impact on a broad range of PROs consistently across various geographic regions.
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Details
- Title
- Atrial arrhythmias and patient-reported outcomes in adults with congenital heart disease: An international study
- Creators
- Benjamin Casteigt - Montreal Heart InstituteMichelle Samuel - Montreal Heart InstituteLaurence Laplante - Montreal Heart InstituteAzadeh Shohoudi - Montreal Heart InstituteSilke Apers - KU LeuvenAdrienne H. Kovacs - Oregon Health & Science UniversityKoen Luyckx - KU LeuvenCorina Thomet - University Hospital of BernWerner Budts - KU LeuvenJunko Enomoto - Chiba Cerebral and Cardiovascular CenterMaayke A. Sluman - Jeroen Bosch ZiekenhuisChun-Wei Lu - National Taiwan University HospitalJamie L. Jackson - Nationwide Children's HospitalStephen C. Cook - Helen DeVos Children's HospitalShanthi Chidambarathanu - Frontier Lifeline HospitalLuis Alday - Division of Cardiology, Hospital de Niños, Córdoba, ArgentinaKatrine Eriksen - Oslo University HospitalMikael Dellborg - Sahlgrenska University HospitalMalin Berghammer - University WestBengt Johansson - Umeå UniversityAndrew S. Mackie - Stollery Children's HospitalSamuel Menahem - Monash Medical CentreMaryanne Caruana - Mater Dei HospitalGruschen Veldtman - Cincinnati Children's Hospital Medical CenterAlexandra Soufi - Hôpital Louis PradelSusan M. Fernandes - Stanford UniversityKamila White - Jewish HospitalEdward Callus - IRCCS Policlinico San DonatoShelby Kutty - Children's Hospital & Medical CenterJudith Brouillette - Montreal Heart InstitutePhilip Moons - KU LeuvenPaul Khairy - Montreal Heart Instituteof the APPROACH-IS Consortium and the International Society for Adult Congenital Heart Disease (ISACHD)
- Publication Details
- Heart rhythm, v 18(5), pp 793-800
- Publisher
- Elsevier
- Number of pages
- 8
- Grant note
- University of Gothenburg (https://doi.org/10.13039/501100005760) Cardiac Children's Foundation (https://doi.org/10.13039/501100002801) Swedish Heart-Lung Foundation (https://doi.org/10.13039/501100003793)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:000717466400021
- Scopus ID
- 2-s2.0-85104281510
- Other Identifier
- 991022135713904721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems