Journal article
Atrial fibrillation detected by mobile cardiac outpatient telemetry in cryptogenic TIA or stroke
Neurology, v 71(21), pp 1696-1701
18 Nov 2008
PMID: 18815386
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective: Atrial fibrillation (AF) may be present within a subset of patients with presumed cryptogenic TIA or stroke and remains undetected by standard diagnostic methods. We hypothesized that AF may be an under-recognized mechanism for cryptogenic TIA/stroke.
Methods: A consecutive series of 56 patients with cryptogenic TIA/stroke was analyzed after diagnostic evaluation and Mobile Cardiac Outpatient Telemetry (MCOT) for up to 21 days. Demographic, radiographic, echocardiographic, and MCOT results were reviewed. Predictors of AF detection by MCOT were determined by univariate analysis including Student t test and Fisher exact tests and multivariate analysis.
Results: The median MCOT monitoring duration was 21 (range 5-21) days resulting in an AF detection rate of 23% (13/56). AF was first detected after a median of 7 (range 2-19) days of monitoring. Twenty-seven asymptomatic AF episodes were detected in the 13 patients, of which 85% (23/27) were <30 seconds and the remaining 15% (4/27) were 4-24 hours in duration. Diabetes was predictive of AF detection by both univariate (p = 0.024) and multivariate analysis (OR 6.15; 95% CI 1.16 to 32.73; p = 0.033).
Conclusions: There is a high rate of atrial fibrillation (AF) detection by Mobile Cardiac Outpatient Telemetry (21 days) in patients with cryptogenic TIA/stroke that may be related to extended monitoring duration, patient selection, and inclusion of all new onset AF episodes. Brief AF episodes (<30 seconds) may be biomarkers of more prolonged and clinically significant AF. Neurology (R) 2008;71:1696-1701
Metrics
Details
- Title
- Atrial fibrillation detected by mobile cardiac outpatient telemetry in cryptogenic TIA or stroke
- Creators
- A. H. Tayal - Allegheny General HospitalM. Tian - Allegheny Gen Hosp, Dept Neurol, Pittsburgh, PA 15260 USAK. M. Kelly - Allegheny Gen Hosp, Dept Neurol, Pittsburgh, PA 15260 USAS. C. Jones - Allegheny Gen Hosp, Dept Neurol, Pittsburgh, PA 15260 USAD. G. Wright - Allegheny Gen Hosp, Dept Neurol, Pittsburgh, PA 15260 USAD. Singh - Allegheny Gen Hosp, Dept Neurol, Pittsburgh, PA 15260 USAJ. Jarouse - Allegheny Gen Hosp, Dept Neurol, Pittsburgh, PA 15260 USAJ. Brillman - Allegheny Gen Hosp, Dept Neurol, Pittsburgh, PA 15260 USAS. Murali - Drexel UniversityR. Gupta - Cleveland Clin Fdn, Dept Neurol, Cleveland, OH USA
- Publication Details
- Neurology, v 71(21), pp 1696-1701
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate); Neurology
- Web of Science ID
- WOS:000260953600008
- Scopus ID
- 2-s2.0-58149269939
- Other Identifier
- 991019168378304721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology