Journal article
Atrial myopathy
Current problems in cardiology, v 49(3), 102381
Mar 2024
PMID: 38191102
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This paper delves into the progressive concept of atrial myopathy, shedding light on its development and its impact on atrial characteristics. It extensively explores the intricate connections between atrial myopathy, atrial fibrillation (AF), and strokes. Researchers have sought additional contributors to AF-related strokes due to the absence of a clear timing correlation between paroxysmal AF episodes and strokes in patients with cardiac implantable electronic devices. Through various animal models and human investigations, a close interrelation among aging, inflammation, oxidative stress, and stretching mechanisms has been identified. These mechanisms contribute to fibrosis, alterations in electrical properties, autonomic remodeling, and a heightened pro-thrombotic state. These interconnected factors establish a detrimental cycle, exacerbating atrial myopathy and elevating the risk of sustained AF and strokes. By emphasizing the significance of atrial myopathy and the risk of strokes that are distinct from AF, the paper also discusses methods for identifying patients with atrial myopathy. Moreover, it proposes an approach to incorporate the concept of atrial myopathy into clinical practice to guide anticoagulation decisions in individuals with AF.
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Details
- Title
- Atrial myopathy
- Creators
- Muhammad Umer Riaz Gondal - Reading HospitalRaja Sadam Mehmood - Shifa International HospitalRahmeen Pervaiz Khan - Shifa International HospitalJahanzeb Malik - Cardiovascular Research Associates
- Publication Details
- Current problems in cardiology, v 49(3), 102381
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:001167395500001
- Scopus ID
- 2-s2.0-85182884800
- Other Identifier
- 991022193968704721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
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- Collaboration types
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems