Journal article
Auditory Characteristics in Children With Enlarged Vestibular Aqueduct
Otology & neurotology, v 46(5), pp 544-551
Jun 2025
PMID: 40164977
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
ObjectiveEnlarged vestibular aqueduct (EVA) is the most common radiographic finding in children diagnosed with congenital sensorineural hearing loss (SNHL). Many institutions use the Cincinnati criteria for diagnosis: width >= 2.0 mm at the operculum and/or >= 1.0 mm at the midpoint. Our goals are to expand our understanding of EVA by examining the audiometric and auditory brainstem response (ABR) characteristics of a large population of children with EVA and hearing loss.Study DesignRetrospective chart review.SettingTertiary-care children's hospital.PatientsAll children diagnosed with EVA from 2006 to 2016.InterventionsDiagnostic.Main Outcome MeasuresVestibular aqueduct measurements were taken at the operculum.ResultsOne hundred six patients were included (63 females; 60 bilateral EVA). The age of hearing loss diagnosis was significantly younger in patients with bilateral EVA compared with unilateral (0.0 [0-3] yr versus 5.0 [0.9-7.0] yr, p = 0.001). The most common pattern seen on ABR was SNHL-like (57%), followed by large wave I pattern (28.6%), followed by auditory neuropathy spectrum disorder (14.3%). Patients with bilateral EVA were more likely to have progressive hearing loss compared with patients with unilateral EVA (p = 0.001). There was no correlation between EVA size and hearing stability or between EVA size and pure-tone average at the time of diagnosis.ConclusionThere is a wide range of clinical manifestations of EVA, though we found no significant correlation between size and progressiveness or severity. The clinical significance of a large wave I tracing on ABR is not fully understood and warrants further research.
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Details
- Title
- Auditory Characteristics in Children With Enlarged Vestibular Aqueduct
- Creators
- Punam Patel - Phoenix Childrens Hosp, Dept Otolaryngol, Phoenix, AZ 85016 USAWilliam Parkes - Nemours Children's Health SystemCedric Pritchett - Nemours Children's ClinicMatthew Stewart - Thomas Jefferson UniversityArabinda Choudhari - SUNY Upstate Medical UniversityRahul Nikam - Children's Hospital of Orange CountyJobayer Hossain - Nemours Children's Health SystemRobert O'Reilly - Childrens Hosp Philadelphia, Div Otolaryngol, Philadelphia, PA USAThierry Morlet - Nemours Children Hosp, Auditory Physiol & Psychoacoust Res Lab, Wilmington, DE USA
- Publication Details
- Otology & neurotology, v 46(5), pp 544-551
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Audiology - Distance
- Web of Science ID
- WOS:001484636900013
- Scopus ID
- 2-s2.0-105001925225
- Other Identifier
- 991022168372204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Otorhinolaryngology