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Avian Influenza Viruses and their Implication for Human Health
Journal article   Peer reviewed

Avian Influenza Viruses and their Implication for Human Health

Donald Kaye and Craig R. Pringle
Clinical infectious diseases, v 40(1), pp 108-112
01 Jan 2005
DOI: https://doi.org/10.1086/427236
PMID: 15614699
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Widespread outbreaks of avian influenza in domestic fowl throughout eastern Asia have reawakened concern that avian influenza viruses may again cross species barriers to infect the human population and thereby initiate a new influenza pandemic. Simultaneous infection of humans (or swine) by avian influenza viruses in the presence of human influenza viruses could theoretically generate novel influenza viruses with pandemic potential as a result of reassortment of genome subunits between avian and mammalian influenza viruses. These hybrid viruses would have the potential to express surface antigens from avian viruses to which the human population has no preexisting immunity. This article reviews current knowledge of the routes of transmission of avian influenza A viruses to humans, places the risk of appearance of a new pandemic influenza virus in perspective, and describes the recently observed epidemiology and clinical syndromes of avian influenza in humans.

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50 citations in Web of Science
66 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Immunology
Infectious Diseases
Microbiology
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