Journal article
Axotomy-induced changes in cytochrome oxidase activity in the cat trochlear nucleus
Brain research, v 637(1)
1994
PMID: 8180806
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Abstract
Following a unilateral section of the trochlear nerve, the effects of axotomy on cytochrome oxidase levels in the trochlear nucleus were studied. Cytochrome oxidase levels in the axotomized nucleus were significantly lower than in the control nucleus. The maximal decrease was observed at 2 weeks. Following partial restoration during weeks 3 and 4, cytochrome oxidase levels stabilized at levels only slightly below normal. Since a significant number of trochlear motoneurons die following axotomy, the restoration of cytochrome oxidase levels close to normal suggests that the surviving neurons may compensate for an increased load with a permanent increase in oxidative metabolism.
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Details
- Title
- Axotomy-induced changes in cytochrome oxidase activity in the cat trochlear nucleus
- Creators
- Pasquale G IannuzzelliXiao H WangYuechu WangE. Hazel Murphy
- Publication Details
- Brain research, v 637(1)
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:A1994MY43600034
- Scopus ID
- 2-s2.0-0027953323
- Other Identifier
- 991014877887704721
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- Web of Science research areas
- Neurosciences