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Bacteremia Due to Bacteroides fragilis after Elective Appendectomy in Renal Transplant Recipients
Journal article   Peer reviewed

Bacteremia Due to Bacteroides fragilis after Elective Appendectomy in Renal Transplant Recipients

Margaret C. Fisher, H. Jorge Baluarte and Sarah S. Long
The Journal of infectious diseases, v 143(5), pp 635-638
May 1981
DOI: https://doi.org/10.1093/infdis/143.5.635
PMID: 7017018
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Bacteremia caused by Bacteroides fragilis occurred in four of 75 children after renal transplantation, and B. fragilis was the most common cause of postoperative bacteremia. Bacteroides bacteremia was significantly associated with performance of elective appendectomy at the time of transplantation (P < 0.01) and with profound lymphocytopenia (P = 0.01). No patient received antibiotics at the time of surgery or prior to the first positive blood culture, yet B. fragilis was the single organism isolated from blood and abscesses in these patients. A role for lymphocytes in containment of B. fragilis has not been suggested previously, although unexplained occurrence of bacteroides bacteremia in immunocompromised patients has occasionally been reported. Lymphocytes themselves may be important in this host-bacterium interaction, or lymphocytopenia may be the marker for a more generalized deficiency in host defenses.

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8 citations in Web of Science
9 citations in Scopus

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#3 Good Health and Well-Being

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Web of Science research areas
Immunology
Infectious Diseases
Microbiology
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