Journal article
Bacteria-inspired nanorobots with flagellar polymorphic transformations and bundling
Scientific reports, v 7(1), pp 14098-10
26 Oct 2017
PMID: 29074862
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Wirelessly controlled nanoscale robots have the potential to be used for both in vitro and in vivo biomedical applications. So far, the vast majority of reported micro- and nanoscale swimmers have taken the approach of mimicking the rotary motion of helical bacterial flagella for propulsion, and are often composed of monolithic inorganic materials or photoactive polymers. However, currently no man-made soft nanohelix has the ability to rapidly reconfigure its geometry in response to multiple forms of environmental stimuli, which has the potential to enhance motility in tortuous heterogeneous biological environments. Here, we report magnetic actuation of self-assembled bacterial flagellar nanorobotic swimmers. Bacterial flagella change their helical form in response to environmental stimuli, leading to a difference in propulsion before and after the change in flagellar form. We experimentally and numerically characterize this response by studying the swimming of three flagellar forms. Also, we demonstrate the ability to steer these devices and induce flagellar bundling in multi-flagellated nanoswimmers.
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Details
- Title
- Bacteria-inspired nanorobots with flagellar polymorphic transformations and bundling
- Creators
- Jamel Ali - Drexel UniversityU. Kei Cheang - Southern University of Science and TechnologyJames D. Martindale - University of UtahMehdi Jabbarzadeh - University of UtahHenry C. Fu - University of UtahMin Jun Kim - Southern Methodist University
- Publication Details
- Scientific reports, v 7(1), pp 14098-10
- Publisher
- Springer Nature
- Number of pages
- 10
- Grant note
- DMR 1712061; CMMI 1737682; DMR 1650970; CBET 1651031 / National Science Foundation; National Science Foundation (NSF) 10052980 / Ministry of Trade, Industry, and Energy (MOTIE) Korea Evaluation Institute of Industrial Technology (KEIT) 32 CFR 168a / DoD, Air Force Office of Scientific Research, National Defense Science and Engineering Graduate (NDSEG); United States Department of Defense; Air Force Office of Scientific Research (AFOSR)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000413816000028
- Scopus ID
- 2-s2.0-85032462423
- Other Identifier
- 991019330626004721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Biochemistry & Molecular Biology