Journal article
Benefit of visual speech information for word comprehension in post-stroke aphasia
CORTEX, v 165
Aug 2023
PMID: 37271014
Abstract
Aphasia is a language disorder that often involves speech comprehension impairments affecting communication. In face-to-face settings, speech is accompanied by mouth and facial movements, but little is known about the extent to which they benefit aphasic comprehension. This study investigated the benefit of visual information accompanying speech for word comprehension in people with aphasia (PWA) and the neuroanatomic substrates of any benefit. Thirty-six PWA and 13 neurotypical matched control participants performed a picture-word verification task in which they indicated whether a picture of an animate/inanimate object matched a subsequent word produced by an actress in a video. Stimuli were either audiovisual (with visible mouth and facial movements) or auditory -only (still picture of a silhouette) with audio being clear (unedited) or degraded (6-band noise-vocoding). We found that visual speech information was more beneficial for neu-rotypical participants than PWA, and more beneficial for both groups when speech was degraded. A multivariate lesion-symptom mapping analysis for the degraded speech condition showed that lesions to superior temporal gyrus, underlying insula, primary and secondary somatosensory cortices, and inferior frontal gyrus were associated with reduced benefit of audiovisual compared to auditory-only speech, suggesting that the integrity of these fronto-temporo-parietal regions may facilitate cross-modal mapping. These findings provide initial insights into our understanding of the impact of audiovisual information on comprehension in aphasia and the brain regions mediating any benefit.& COPY; 2023 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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Details
- Title
- Benefit of visual speech information for word comprehension in post-stroke aphasia
- Publication Details
- CORTEX, v 165
- Publisher
- ELSEVIER MASSON, CORP OFF; PARIS
- Grant note
- We would like to thank Erica Middleton for sharing picture stimuli with us; Rachel Metzgar for helping with recruitment and testing; Frank Garcea for his expertise in lesion-symptom mapping analysis; H. Branch Coslett for help with lesion segmentation; Linda Drijvers for sharing the Praat script; and all participants who took part in our study. This research was supported by Peer Review Committee funding (PRC FY19-2) awarded to LB and GV. The work was further supported by a European Research Council Advanced Grant (ECOLANG, 743035). While working on this project, GV was supported by a Royal Society Wolfson Research Merit Award (WRM\R3\170016). This research was also supported by the UCL Bogue Research Fellowship awarded to AK.
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:001015133200001
- Scopus ID
- 2-s2.0-85163406658
- Other Identifier
- 991021861278204721
InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Behavioral Sciences
- Neurosciences
- Psychology, Experimental