Journal article
Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure
Bioanalysis, Vol.7(9), pp.1157-1173
01 May 2015
PMCID: PMC4487641
PMID: 26039812
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Asbestos exposure is known to cause lung cancer and mesothelioma and its health and economic impacts have been well documented. The exceptionally long latency periods of most asbestos-related diseases have hampered preventative and precautionary steps thus far. We aimed to summarize the state of knowledge on biomarkers of response to asbestos exposure. Asbestos is not present in human biological fluids; rather it is inhaled and trapped in lung tissue. Biomarkers of response, which reflect a change in biologic function in response to asbestos exposure, are analyzed. Several classes of molecules have been studied and evaluated for their potential utility as biomarkers of asbestos exposure. These studies range from small molecule oxidative stress biomarkers to proteins involved in immune responses.
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Details
- Title
- Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure
- Creators
- Clementina Mesaros - University of PennsylvaniaAndrew J Worth - University of PennsylvaniaNathaniel W Snyder - University of PennsylvaniaMelpo Christofidou-Solomidou - Drexel UniversityAnil Vachani - Drexel UniversitySteven M Albelda - Drexel UniversityIan A Blair - University of Pennsylvania
- Publication Details
- Bioanalysis, Vol.7(9), pp.1157-1173
- Publisher
- Future Science Ltd
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- A.J. Drexel Autism Institute
- Identifiers
- 991019167895204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biochemical Research Methods
- Chemistry, Analytical