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Biomaterials for the central nervous system
Journal article   Open access

Biomaterials for the central nervous system

Yinghui Zhong and Ravi V Bellamkonda
Journal of the Royal Society interface, v 5(26), pp 957-975
06 Sep 2008
PMID: 18477539
url
https://doi.org/10.1098/rsif.2008.0071View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural stem cell encapsulation for neurotrauma. The biological and material requirements for the biomaterials in these applications are discussed. The difficulties that the biomaterials might face in each application and the possible solutions are also reviewed in this article.

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Domestic collaboration
Web of Science research areas
Neurosciences
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