Files and links (1)
Accepted (AM)Open Access (License Unspecified), Open
Journal article
Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia
The Journal of pediatrics, v 207, pp 130-135
Apr 2019
PMID: 30612812
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To use a large current prospective cohort of infants <29 weeks to compare bronchopulmonary dysplasia (BPD) rates in black and white infants.
The Prematurity and Respiratory Outcome Program (PROP) enrolled 835 infants born in 2011-2013 at <29 weeks of gestation; 728 black or white infants survived to 36 weeks postmenstrual age (PMA). Logistic regression was used to compare BPD outcomes (defined as supplemental oxygen requirement at 36 weeks PMA) between the races, adjusted for gestational age (GA), antenatal steroid use, intubation at birth, and surfactant use at birth.
Of 707 black or white infants with available BPD outcomes, BPD was lower in black infants (38% vs 45%), even though they were of significantly lower GA. At every GA, BPD was more common in white infants. The aOR for BPD was 0.60 (95% CI, 0.42-0.85; P = .004) for black infants compared with white infants after adjusting for GA. Despite the lower rate of BPD, black infants had a higher rate of first-year post-prematurity respiratory disease (black, 79%; white, 63%).
In this large cohort of recently born preterm infants at <29 weeks GA, compared with white infants, black infants had a lower risk of BPD but an increased risk of persistent respiratory morbidity.
Metrics
Details
- Title
- Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia
- Creators
- Rita M. Ryan - Department of Pediatrics, Medical University of South Carolina, Charleston, SCRui Feng - University of PennsylvaniaCatalina Bazacliu - Department of Pediatrics, University of Florida, Gainesville, FLThomas W. Ferkol - Department of Pediatrics, Washington University, St. Louis, MOClement L. Ren - Division of Pediatric Pulmonology, Allergy and Sleep Medicine, Department of Pediatrics, Indiana University, Indianapolis, INThomas J. Mariani - Department of Pediatrics, University of Rochester, Rochester, NYBrenda B. Poindexter - Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OHFan Wang - Department of Molecular Cardiology, Lerner Research Institute, The Cleveland Clinic, Cleveland, OHPaul E. Moore - Department of Pediatrics, Vanderbilt University, Nashville, TNClaire Chougnet - Cincinnati Children's Hospital Medical CenterJames M. Greenberg - Cincinnati Children's Hospital Medical CenterWilliam Hardie - Cincinnati Children's Hospital Medical CenterAlan H. Jobe - Cincinnati Children's Hospital Medical CenterKaren McDowell - Cincinnati Children's Hospital Medical CenterAaron Hamvas - Washington University School of MedicineMark R. Holland - Washington University School of MedicineJames Kemp - Washington University School of MedicinePhilip T. Levy - Washington University School of MedicineChristopher McPherson - Washington University School of MedicinePhillip Tarr - Washington University School of MedicineGautam K. Singh - Washington University School of MedicineBarbara Warner - Washington University School of MedicinePhilip L. Ballard - University of California-San FranciscoRoberta A. Ballard - University of California-San FranciscoDavid J. Durand - University of California-San FranciscoEric C. Eichenwald - University of California-San FranciscoAmir M. Khan - University of California-San FranciscoLeslie Lusk - University of California-San FranciscoJeffrey D. Merrill - University of California-San FranciscoDennis W. Nielson - University of California-San FranciscoElizabeth E. Rogers - University of California-San FranciscoJudy Aschner - Vanderbilt UniversityCandice Fike - Vanderbilt UniversityScott Guthrie - Vanderbilt UniversityTina Hartert - Vanderbilt UniversityNathalie Maitre - Vanderbilt UniversityMarshall Summar - Vanderbilt UniversityCarl T. D'Angio - University of RochesterVasanth Kumar - University of RochesterGloria Pryhuber - University of RochesterAnne Marie Reynolds - University of RochesterKristin Scheible - University of RochesterTimothy Stevens - University of RochesterC. Michael Cotten - Duke UniversityKim Fisher - Duke UniversityJack Sharp - Duke UniversityJudith A. Voynow - Duke UniversityStephanie Davis - Indiana UniversityScarlett A. Bellamy - University of PennsylvaniaJonas Ellenberg - University of Pennsylvania, DCCMelissa Fernando - University of Pennsylvania, DCCHoward Panitch - University of Pennsylvania, DCCPamela A. Shaw - University of Pennsylvania, DCCBarbara Schmidt - University of Pennsylvania, DCCLynn M. Taussig - Drexel UniversityCarol J. Blaisdell - Drexel UniversityPrematurity and Respiratory Outcome Program (PROP) Investigators
- Publication Details
- The Journal of pediatrics, v 207, pp 130-135
- Publisher
- Elsevier
- Grant note
- U01 HL101456 / University of Pennsylvania (http://dx.doi.org/10.13039/100006920) U01 HL101800 / Washington University U01 HL101813 / University of California San Francisco 5R01 HL105702 / Cincinnati Children's Hospital Medical Center (http://dx.doi.org/10.13039/100007172) University of Rochester (http://dx.doi.org/10.13039/100008091) Indiana University (http://dx.doi.org/10.13039/100006733) U01 HL101798 / Vanderbilt University (http://dx.doi.org/10.13039/100006537) U01 HL101794 / National Institutes of Health (http://dx.doi.org/10.13039/100000002) Duke University (http://dx.doi.org/10.13039/100006510) U01 HL101465 / University at Buffalo (http://dx.doi.org/10.13039/100008209)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000462161200026
- Scopus ID
- 2-s2.0-85059510000
- Other Identifier
- 991019298996004721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Pediatrics