Journal article
Bladder cancer and drinking water: a population-based case-control study in Washington County, Maryland (United States)
Cancer causes & control, v 8(5), pp 738-744
Sep 1997
PMID: 9328196
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A population-based case-control study was conducted in WashingtonCounty, Maryland (United States) to explore the association between incidentbladder cancer and exposure to drinking water from chlorinated surfacesources. Cancer cases were White residents, enumerated in a 1975 countycensus and reported to the Washington County Cancer Registry (n = 294)between 1975 and 1992. White controls, frequency matched by age (± 5 years)and gender, were selected randomly from the census (n = 2,326). Householdsreceiving municipal water, which generally derived from chlorinated surfacewaters, were treated as having ‘high exposure‘ and all others, as ‘lowexposure.’ Duration of exposure to type of drinking water was based on lengthof residence in the census household prior to 1975. Odds ratios (OR) werecalculated using logistic regression methods, adjusting for age, gender,tobacco use, and urbanicity. Bladder cancer risk was associated weakly in thegeneral population with duration o f exposure to municipal water. Theassociation was limited to those who had smoked cigarettes. In ever-smokerscompared with never-smokers with low exposure, the adjusted ORs for bladdercancer risk with increasing exposure were 1.3, 1.4, 1.4, 1.7, 2.2, 2.8,respectively, for 0, 1-10, 11-20, 21-30, 31-40, > 40 years' exposureduration. The ORs in smokers were not diminished after adjusting for smokinghistory and intensity.
Metrics
Details
- Title
- Bladder cancer and drinking water: a population-based case-control study in Washington County, Maryland (United States)
- Creators
- D Freedman - Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda USAK Cantor - Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda USAN Lee - Johns Hopkins School of Hygiene and Public Health Baltimore USAL.-S Chen - Johns Hopkins School of Hygiene and Public Health Baltimore USAH.-H Lei - Johns Hopkins School of Hygiene and Public Health Baltimore USAC Ruhl - Johns Hopkins School of Hygiene and Public Health Baltimore USAS Wang - Johns Hopkins School of Hygiene and Public Health Baltimore USA
- Publication Details
- Cancer causes & control, v 8(5), pp 738-744
- Publisher
- Kluwer Academic Publishers; Dordrecht
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:A1997XX82500008
- Scopus ID
- 2-s2.0-0030850651
- Other Identifier
- 991014877835404721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Oncology
- Public, Environmental & Occupational Health