Journal article
Blockade of GABA A receptors in the medial ventral pallidum elicits feeding in satiated rats
Brain research, v 825(1)
1999
PMID: 10216189
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
γ-aminobutyric acid (GABA)-containing fibers from the nucleus accumbens shell (AcbSh) terminate in the medial ventral pallidum (VPm) and neurons in the VPm project to the lateral hypothalamus (LH). Therefore, the VPm is anatomically interposed between the AcbSh and LH, two functionally related brain regions that mediate food intake. The present study demonstrates that blockade of GABA
A receptors in the VPm by local administration of bicuculline greatly increases food intake in satiated rats. The data suggest that an AcbSh-VPm-LH circuit may be involved in the control of feeding behavior.
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Details
- Title
- Blockade of GABA A receptors in the medial ventral pallidum elicits feeding in satiated rats
- Creators
- Thomas R. Stratford - Hahnemann University HospitalAnn E. Kelley - University of Wisconsin–MadisonKenny J. Simansky - Hahnemann University Hospital
- Publication Details
- Brain research, v 825(1)
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pharmacology and Physiology
- Web of Science ID
- WOS:000079954500022
- Scopus ID
- 2-s2.0-0033577366
- Other Identifier
- 991019168648104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Neurosciences