Journal article
Blockade of GABA sub(A) receptors in the medial ventral pallidum elicits feeding in satiated rats
Brain research, Vol.825(1-2)
17 Apr 1999
Abstract
gamma -Aminobutyric acid (GABA)-containing fibers from the nucleus accumbens shell (AcbSh) terminate in the medial ventral pallidum (VPm) and neurons in the VPm project to the lateral hypothalamus (LH). Therefore, the VPm is anatomically interposed between the AcbSh and LH, two functionally related brain regions that mediate food intake. The present study demonstrates that blockade of GABA sub(A) receptors in the VPm by local administration of bicuculline greatly increases food intake in satiated rats. The data suggest that an AcbSh-VPm-LH circuit may be involved in the control of feeding behavior.
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Details
- Title
- Blockade of GABA sub(A) receptors in the medial ventral pallidum elicits feeding in satiated rats
- Creators
- T StratfordA KelleyK Simansky
- Publication Details
- Brain research, Vol.825(1-2)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- SOM Dean - Research Administration
- Identifiers
- 991021842530504721