Journal article
Body Mass Index and Mortality in Cardiogenic Shock
ASAIO journal (1992), v 70(10), pp 885-891
Oct 2024
PMID: 38527077
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We explored the association of body mass index (BMI) with mortality in cardiogenic shock (CS). Using the Cardiogenic Shock Working Group registry, we assessed the impact of BMI on mortality using restricted cubic splines in a multivariable logistic regression model adjusting for age, gender, and race. We also assessed mortality, device use, and complications in BMI categories, defined as underweight (<18.5 kg/m 2 ), normal (18.5–24.9 kg/m 2 ), overweight (25–29.9 kg/m 2 ), obese (30–39.9 kg/m 2 ), and severely obese (>40 kg/m 2 ) using univariable logistic regression models. Our cohort had 3,492 patients with CS (mean age = 62.1 ± 14 years, 69% male), 58.0% HF-related CS (HF-CS), and 27.8% acute myocardial infarction (AMI) related CS. Body mass index was a significant predictor of mortality in multivariable regression using restricted cubic splines ( p < 0.0001, p = 0.194 for nonlinearity). When stratified by categories, patients with healthy weight had lower mortality (29.0%) than obese (35.1%, p = 0.003) or severely obese (36.7%, p = 0.01). In HF-CS cohort, the healthy weight patients had the lowest mortality (21.7%), whereas it was higher in the underweight (37.5%, p = 0.012), obese (29.2%, p = 0.003), and severely obese (29.9%, p = 0.019). There was no difference in mortality among BMI categories in AMI-CS.
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Details
- Title
- Body Mass Index and Mortality in Cardiogenic Shock
- Creators
- Maya Guglin - Indiana University HealthElric Zweck - Heinrich Heine University DüsseldorfManreet Kanwar - Allegheny Health NetworkShashank S. Sinha - Inova Fairfax HospitalArvind Bhimaraj - Houston MethodistBorui Li - Tufts Medical CenterJacob Abraham - Hope Heart InstituteSaraschandra Vallabhajosyula - Brown UniversityJaime Hernandez-Montfort - Baylor Scott & White HealthRachna Kataria - Brown UniversityDaniel Burkhoff - Cardiovascular Research FoundationNavin K. Kapur - Tufts Medical Centeron the behalf of the Cardiogenic Shock Working Group
- Publication Details
- ASAIO journal (1992), v 70(10), pp 885-891
- Publisher
- Lippincott
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Cardiology
- Web of Science ID
- WOS:001325218700018
- Scopus ID
- 2-s2.0-85205403227
- Other Identifier
- 991021932194004721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Engineering, Biomedical
- Transplantation