Logo image
Back
Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community
Journal article   Open access   Peer reviewed

Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community

D. Keating, C.G. Zundel, M. Abreu, M. Krengel, K. Aenlle, M.D. Nichols, R. Toomey, L.L. Chao, J. Golier, L. Abdullah, …
Life sciences (1973), v 284, 119903
01 Nov 2021
DOI: https://doi.org/10.1016/j.lfs.2021.119903
PMID: 34453948
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1016/j.lfs.2021.119903View
Published, Version of Record (VoR)CC BY V4.0,  Open

Abstract

BBRAIN Gulf war Gulf war illness GWI GWIC
Gulf War Illness (GWI), a chronic debilitating disorder characterized by fatigue, joint pain, cognitive, gastrointestinal, respiratory, and skin problems, is currently diagnosed by self-reported symptoms. The Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) is the collaborative effort of expert Gulf War Illness (GWI) researchers who are creating objective diagnostic and pathobiological markers and recommend common data elements for GWI research. BBRAIN is recruiting 300 GWI cases and 200 GW veteran controls for the prospective study. Key data and biological samples from prior GWI studies are being merged and combined into retrospective datasets. They will be made available for data mining by the BBRAIN network and the GWI research community. Prospective questionnaire data include general health and chronic symptoms, demographics, measures of pain, fatigue, medical conditions, deployment and exposure histories. Available repository biospecimens include blood, plasma, serum, saliva, stool, urine, human induced pluripotent stem cells and cerebrospinal fluid. To date, multiple datasets have been merged and combined from 15 participating study sites. These data and samples have been collated and an online request form for repository requests as well as recommended common data elements have been created. Data and biospecimen sample requests are reviewed by the BBRAIN steering committee members for approval as they are received. The BBRAIN repository network serves as a much needed resource for GWI researchers to utilize for identification and validation of objective diagnostic and pathobiological markers of the illness.

Metrics

18 Record Views
8 citations in Web of Science
8 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Medicine, Research & Experimental
Pharmacology & Pharmacy
Logo image