Journal article
Botulinum Toxin Injections Into the Lateral Cricoarytenoid Muscles for Vocal Process Granuloma
Journal of voice, v 32(3), pp 363-366
May 2018
PMID: 28778373
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Contact granulomas are benign, exophytic inflammatory lesions of the larynx that typically arise on or near the vocal process of the arytenoid cartilage. The most common management options include voice therapy and antireflux pharmacotherapy, intralesional steroid injections, botulinum toxin injections, and surgical excision. In-office Botox injection into the lateral cricoarytenoid (LCA) muscle can be effective even for recurrent granulomas.
This is a retrospective chart review and literature review.
We reviewed more than 400 charts and included two patients, who underwent in-office injection with botulinum toxin A into LCA muscles bilaterally, after previously failing both conservative and surgical management.
Both cases showed significant improvement of the laryngeal granulomas after 6 months and a single botulinum toxin injection. Both cases were initially grade III granuloma that improved to grade I.
In-office injection of botulinum toxin A targeting the LCA muscle appears to be a safe and effective treatment modality in refractory laryngeal granuloma.
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Details
- Title
- Botulinum Toxin Injections Into the Lateral Cricoarytenoid Muscles for Vocal Process Granuloma
- Creators
- Q. Pham - Philadelphia College of Osteopathic MedicineR. Campbell - University of OttawaJ. Mattioni - Philadelphia College of Osteopathic MedicineR. Sataloff - Drexel University
- Publication Details
- Journal of voice, v 32(3), pp 363-366
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000432462500017
- Scopus ID
- 2-s2.0-85026500181
- Other Identifier
- 991019312382404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Audiology & Speech-language Pathology
- Otorhinolaryngology