Journal article
Bowel preparation prior to minimally invasive sacrocolpopexy: a randomized controlled trial
International Urogynecology Journal, v 31(7), pp 1305-1313
01 Jul 2020
PMID: 31773199
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Introduction and hypothesis
The objective was to determine if a bowel preparation prior to minimally invasive sacrocolpopexy (MIS) influences post-operative constipation symptoms. We hypothesized that women who underwent a bowel preparation would have an improvement in post-operative defecatory function.
Methods
In this randomized controlled trial, women undergoing MIS received a pre-operative bowel preparation or no bowel preparation. Our primary outcome was post-operative constipation measured by the Patient Assessment of Constipation Symptoms (PAC-SYM) 2 weeks post-operatively. Secondary outcomes included surgeon’s perception of case difficulty. Both intention-to-treat (ITT) and per-protocol analyses (PPA) were performed. Analyses were carried out using
t
test, Fisher’s exact test, the Wilcoxon test and the Chi-squared test.
Results
Of 105 enrolled women, 95 completed follow-up (43 preparation and 52 no preparation). Baseline characteristics and rates of complications were similar. No differences were noted on ITT. The post-operative abdominal PAC-SYM subscale was closer to baseline for women who received a bowel preparation on PPA (change in score 0.74 vs 1.08,
p
= 0.045). Women who underwent a preparation were less likely to report strain (6.0% vs 26.7%,
p
= 0.009) or type 1 Bristol stool on their first post-operative bowel movement (4.3% vs 17.5%,
p
= 0.047). Surgeons were more likely to rate the complexity of the case as “more difficult than average” (54.4% vs 40.1%,
p
= 0.027) in those without a bowel preparation.
Conclusions
Although there was no difference in ITT analysis, women who underwent a bowel preparation prior to MIS demonstrated benefit to post-operative defecatory function with a corresponding improvement in surgeon’s perception of case complexity.
Metrics
8 Record Views
Details
- Title
- Bowel preparation prior to minimally invasive sacrocolpopexy: a randomized controlled trial
- Creators
- Jessica C. Sassani - Magee-Womens HospitalKelly Kantartzis - Banner - University Medical Center TucsonLiwen Wu - University of PittsburghAnthony Fabio - University of PittsburghHalina M. Zyczynski - Magee-Womens Hospital
- Publication Details
- International Urogynecology Journal, v 31(7), pp 1305-1313
- Publisher
- Springer International Publishing
- Number of pages
- 9
- Grant note
- UL1TR001857 / National Institutes of Health (http://dx.doi.org/10.13039/100000002)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Obstetrics and Gynecology
- Web of Science ID
- WOS:000544356200004
- Scopus ID
- 2-s2.0-85075613898
- Other Identifier
- 991022135715504721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Obstetrics & Gynecology
- Urology & Nephrology