Journal article
Breast cancer stage at time of detection in women with systemic lupus erythematosus
Lupus, v 13(6), pp 469-472
01 Jan 2004
PMID: 15303575
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Mounting evidence suggests an increased cancer risk in several autoimmune diseases, including systemic lupus erythematosus (SLE). However, greater scrutiny for cancer in subjects with chronic disease (compared to the general population) might explain this apparent association. If so, one would expect cancers in SLE to be diagnosed at earlier stages than in the general population. This might be particularly evident in cancers where screening is available, such as breast cancer. We linked the University of Pittsburgh lupus cohort with the Pennsylvania Cancer Registry to determine the frequency distribution for stage at diagnosis of invasive breast cancers in the SLE subjects. Data on staging of cancers occurring in the general population of Pennsylvania were obtained from The US Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute. A lower percentage of women with SLE presented with localized breast cancer (nine of the 16, 56.2%) compared to the general population of women (63.5%). Although not definitive, this evidence suggests that cancers in SLE are not necessarily diagnosed at earlier stages than in the general population.
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Details
- Title
- Breast cancer stage at time of detection in women with systemic lupus erythematosus
- Creators
- S Bernatsky - Montreal General HospitalA Clarke - Montreal General HospitalR Ramsey-Goldman - Northwestern UniversityJ-F Boivin - McGill UniversityL Joseph - McGill UniversityRaghu Rajan - Montreal General HospitalS Manzi - University of Pittsburgh
- Publication Details
- Lupus, v 13(6), pp 469-472
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:000222479100009
- Scopus ID
- 2-s2.0-3142694073
- Other Identifier
- 991021934005604721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Rheumatology