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Journal article
Burden of Uncontrolled Hyperglycemia and Its Association with Patients Characteristics and Socioeconomic Status in Philadelphia, USA
Health equity, v 4(1), pp 525-532
01 Jan 2020
PMID: 34095699
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose: To examine the burden of uncontrolled hyperglycemia in patients with diabetes mellitus (DM) and their characteristics in a large urban city. Methods: A randomized sample of 4993 patients with DM >= 18 years old who received routine health care in a large university teaching hospital in the city of Philadelphia was analyzed. Uncontrolled hyperglycemia was classified as blood hemoglobin A1c >8%. The associations of uncontrolled hyperglycemia with sociodemographic and cardiovascular factors were analyzed using univariate and multivariate analysis methods. Results: The results show that patients 18-54 years had the highest prevalence of uncontrolled hyperglycemia (36.0%), followed by those at age 55-64 (30.9%), 65-74 (22.9%), and >= 75 (20.6%) years (p<0.0001). Unadjusted hyperglycemia was significantly associated with patients with increased total cholesterol to high-density lipoprotein ratio (odds ratio [OR]=1.59, 95% confidence interval [CI]: 1.33-1.90, p<0.001), and with prevalent coronary heart disease (OR=1.39, 95% CI: 1.16-1.67, p=0.001). Patients living in neighborhoods with lower socioeconomic status (SES) had significantly higher uncontrolled hyperglycemia rates across the city (r=0.52, R-2=0.27, p=0.03). Conclusions: Findings of this study is one of the first studies to address that younger adults had higher rates of uncontrolled hyperglycemia. Further attention should be paid to the challenges of controlling DM in younger adults and patients who live in neighborhoods with lower SES.
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Details
- Title
- Burden of Uncontrolled Hyperglycemia and Its Association with Patients Characteristics and Socioeconomic Status in Philadelphia, USA
- Creators
- Longjian Liu - Drexel UniversityFengge Wang - Drexel UniversityEdward J. Gracely - Drexel UniversityKari Moore - Drexel UniversitySteven Melly - Drexel UniversityFengqing Zhang - Florida State UniversityPriscila Y. Sato - Drexel UniversityHoward J. Eisen - Division of Cardiology, Penn State University Heart and Vascular Institute, Hershey, Pennsylvania, USA.
- Publication Details
- Health equity, v 4(1), pp 525-532
- Publisher
- Mary Ann Liebert, Inc
- Number of pages
- 8
- Grant note
- 282842 / Drexel University Urban Health Collaborative
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology); MD (Doctor of Medicine) Program; Pharmacology and Physiology; Epidemiology and Biostatistics
- Web of Science ID
- WOS:000616288900003
- Scopus ID
- 2-s2.0-85098972757
- Other Identifier
- 991019168259804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health