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C-alkylation reactions of phenylsulphonylnitromethane. A convenient new α-nitro-sulphone synthesis
Journal article

C-alkylation reactions of phenylsulphonylnitromethane. A convenient new α-nitro-sulphone synthesis

Peter A Wade, Scott D Morrow, Steven A Hardinger, Mallory S Saft and Harry R Hinney
Journal of the Chemical Society, Chemical Communications, (6)
1980

Abstract

Phenylsulphonylnitromethane ( 1 ) is C -alkylated by benzylic halides and primary alkyl iodides affording α -nitro-sulphones in 43-75% yield; α -nitro-sulphones (83-90% yield) are also obtained from the corresponding C -alkylation of allylic acetates in the presence of catalytic Pd(PPh 3 ) 4 .

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