Journal article
Caloric compensation and eating in the absence of hunger in 5-to 12-y-old weight-discordant siblings
The American journal of clinical nutrition, v 96(3), pp 574-583
01 Sep 2012
PMID: 22854400
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background: An impaired ability to compensate for calories and increased eating in the absence of hunger (EAR) has been associated with increased energy intake and weight gain in unrelated children.
Objective: The aims of this study were to compare caloric compensation [the percentage compensation index (%COMPX)] and EAH in weight-discordant siblings aged 5-12 y.
Design: In a crossover, behavioral genetics design, 47 same-sex sibling pairs (53% female, 55% full siblings) were served dinner once a week for 3 wk. Across conditions, siblings were served the same dinner, but 25 min before dinner, they either consumed in full or did not consume 1 of 2 preloads that varied in energy density (ED; 0.57 or 0.97 kcal/g). On the day when no preload was consumed, EAH was assessed after dinner and defined as the number of calories consumed from snacks.
Results: Overweight/obese siblings undercompensated [%COMPX: -48.8 +/- 56.3 (mean +/- SEM)] and therefore overate after the high-ED preload, whereas normal-weight siblings showed accurate compensation (%COMPX: 101.3 +/- 51.9; P = 0.03). Furthermore, overweight/obese siblings consumed 34% more calories (93 kcal) in the absence of hunger than did normal-weight siblings (P = 0.01). Within-pair resemblances for %COMPX and EAH were stronger for full siblings (P < 0.049) than for half siblings (P > 0.23).
Conclusions: An impaired ability to regulate short-term energy intake, which includes incomplete adjustment for calorie differences in a preload and eating when satiated, may represent a behavioral phenotype for obesity in children. Future studies should test whether teaching children to focus on internal satiety cues may prevent at-risk children from overeating. This trial was registered at clinicaltrials.gov as NCT01598389. Am J Clin Nutr 2012;96:574-83.
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Details
- Title
- Caloric compensation and eating in the absence of hunger in 5-to 12-y-old weight-discordant siblings
- Creators
- Tanja V. E. Kral - Univ Penn, Sch Nursing, Dept Biobehav Hlth Sci, Philadelphia, PA 19104 USADavid B. Allison - University of AlabamaLeann L. Birch - Pennsylvania State UniversityVirginia A. Stallings - Childrens Hosp Philadelphia, Div Gastroenterol Hepatol & Nutr, Philadelphia, PA 19104 USARenee H. Moore - College Station Medical CenterMyles S. Faith - Univ N Carolina, Dept Nutr, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
- Publication Details
- The American journal of clinical nutrition, v 96(3), pp 574-583
- Publisher
- AMER SOC NUTRITION-ASN
- Number of pages
- 10
- Grant note
- K01DK078601 / National Institute of Diabetes and Digestive and Kidney Diseases of the NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) P30DK056336 / NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000307863800017
- Scopus ID
- 2-s2.0-84865344426
- Other Identifier
- 991021448155604721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Nutrition & Dietetics