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Cancer Immunotherapy: PD‐1 Blockade Cellular Vesicles for Cancer Immunotherapy (Adv. Mater. 22/2018)
Journal article   Peer reviewed

Cancer Immunotherapy: PD‐1 Blockade Cellular Vesicles for Cancer Immunotherapy (Adv. Mater. 22/2018)

Xudong Zhang, Chao Wang, Jinqiang Wang, Quanyin Hu, Benjamin Langworthy, Yanqi Ye, Wujin Sun, Jing Lin, Tianfu Wang, Jason Fine, …
Advanced materials (Weinheim), v 30(22), 1870152
01 May 2018
url
https://doi.org/10.1002/adma.201870152View
Published, Version of Record (VoR) Restricted

Abstract

cancer immunotherapy cell therapy drug delivery immune checkpoint blockade nanomedicine
In article number 1707112, Peng Huang, Zhen Gu, and co‐workers engineer cellular nanovesicles presenting PD‐1 receptors on their membranes, which enhance antitumor response by disrupting the PD‐1/PD‐L1 immune inhibitory axis. These nanovesicles could also be adapted to carry a variety of therapeutics to achieve synergistic cancer therapy.

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