Journal article
Cancer of the vulva: 2025 update: FIGO Cancer Report 2025
International journal of gynecology and obstetrics
30 Jul 2025
PMID: 40735881
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Vulvar cancer is an uncommon gynecological malignancy primarily affecting postmenopausal women. No specific screening exists and the most effective strategy to reduce the incidence of vulvar cancer is the opportune treatment of predisposing and preneoplastic lesions associated with its development. Although vulvar cancer may be asymptomatic, most women present with vulvar pruritus or pain or have noticed a lump or ulcer. Therefore, any suspicious vulvar lesion should be biopsied to exclude invasion. Once established, the most common subtype is squamous cell carcinoma. The treatment of vulvar cancer depends primarily on histology, clinical, radiological, or surgical staging. Treatment is predominantly surgical and/or adjuvant radiation therapy, particularly for squamous cell carcinoma, although definitive concurrent chemoradiation is an effective alternative, particularly for advanced tumors. In those cases where vulvar cancer presents with distant metastases, systemic therapy is modeled after cervical cancer, a more common cancer where there is more robust data to guide treatment. Management should be individualized and carried out by a multidisciplinary team in a cancer center experienced in the treatment of these tumors.
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Details
- Title
- Cancer of the vulva: 2025 update: FIGO Cancer Report 2025
- Creators
- Alexander B Olawaiye - University of PittsburghMauricio A Cuello - Pontificia Universidad Católica de ChileSushil Beriwal - Allegheny Health NetworkLinda J Rogers - Groote Schuur Hospital
- Publication Details
- International journal of gynecology and obstetrics
- Publisher
- WILEY; HOBOKEN
- Number of pages
- 12
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:001540271100001
- Scopus ID
- 2-s2.0-105012134037
- Other Identifier
- 991022071495404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Obstetrics & Gynecology