Logo image
Back
Candida glabrata complicating in vitro pregnancy: successful management of subsequent pregnancy
Journal article   Open access   Peer reviewed

Candida glabrata complicating in vitro pregnancy: successful management of subsequent pregnancy

Obehi A Asemota, Paul Nyirjesy, Rachel Fox and Jack D Sobel
Fertility and sterility, v 95(2), pp 803.e1-803.e2
Feb 2011
DOI: https://doi.org/10.1016/j.fertnstert.2010.07.1095
PMID: 20840882
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1111/j.1553-2712.2009.00430.xView
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze),  Open

Abstract

Adult Antifungal Agents - therapeutic use Boric Acids - therapeutic use Candida glabrata - physiology Candidiasis - complications Candidiasis - drug therapy Female Fertilization in Vitro Fetal Death - prevention & control Humans Parity Pregnancy Pregnancy Complications, Infectious - diagnosis Pregnancy Complications, Infectious - drug therapy Pregnancy, Multiple - physiology Treatment Outcome Twins
To report the occurrence of Candida glabrata chorioamnionitis complicating an in vitro fertilization (IVF) pregnancy. Case report. University hospital. A 30-year-old woman, primagravida, with an IVF dichorionic-diamniotic pregnancy who presented at 15 weeks with vaginal bleeding. Before embryo transfer in next IVF cycle, vaginal culture from the patient revealed colonization with C. glabrata, which was treated with boric acid. Subsequent pregnancy after eradication of fungal organisms. The patient's first pregnancy was treated with indomethacin and broad-spectrum antibiotics, but her membranes ruptured, and she delivered both twins at 16 weeks; the autopsy and pathology reports were consistent with C. glabrata chorioamnionitis. After boric acid treatment eradicated the organisms, two embryos were transferred in subsequent IVF treatment; the second pregnancy was uncomplicated, with dichorionic-diamniotic twins, delivered by cesarean section at 38 weeks. Eradication of vaginal colonization with C. glabrata may prevent infection of the next IVF pregnancy.

Metrics

20 Record Views
15 citations in Web of Science
17 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
Web of Science research areas
Obstetrics & Gynecology
Reproductive Biology
Logo image