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Carbon-13 Fourier transform nuclear magnetic resonance studies of peptides
Journal article   Peer reviewed

Carbon-13 Fourier transform nuclear magnetic resonance studies of peptides

Murray H. Freedman, Jack S. Cohen and Irwin M. Chaiken
Biochemical and biophysical research communications, v 42(6), pp 1148-1155
1971
PMID: 5550801

Abstract

The carbon-13 nuclear magnetic resonance (CMR) spectra of several small peptides have been obtained at 25.1 MHz and natural abundance of 13C using the Fourier transform technique with proton noise decoupling. Chemical shift values have been studied as a function of pH. The peptide corresponding to the 1–15 sequence of ribonuclease has been synthesized both with normal and 15% 13C enriched Phe in position 8, and the CMR spectra of these two products are compared.

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