Journal article
Carcinoembryonic Antigen Elevation Due to Bowel Sequestration With Mucocele Formation Following Colonic Resection
Archives of pathology & laboratory medicine (1976), v 127(10), pp 1376-1379
01 Oct 2003
PMID: 14521450
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Abstract
Carcinoembryonic antigen (CEA) is recommended as a serologic marker to monitor colorectal carcinoma recurrence. Elevations of CEA due to causes other than carcinoma exist and may lead to a misdiagnosis of recurrent carcinoma. We report a case of bowel sequestration with mucocele formation at the site of previous colo-colic anastomosis causing a mild elevation in CEA. The patient exhibited increasing CEA levels 6 years after resection of a sigmoid colon carcinoma with end-to-end anastomosis. Subsequently, computed tomographic and positron emission tomographic scans documented the presence of a cystic mass showing increased uptake at the anastomotic site. At exploratory laparotomy a mass lesion with mucus-filled protrusions was resected. Pathologic examination documented the presence of sequestration of a segment of the bowel wall with a mucocele and no overlying defect at the mucosal anastomotic site by demonstrating the presence of all bowel layers. After resection of the lesion, the CEA level normalized.
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Details
- Title
- Carcinoembryonic Antigen Elevation Due to Bowel Sequestration With Mucocele Formation Following Colonic Resection
- Creators
- Marian M. Haber - Drexel UniversityMarino E. Leon - Drexel UniversityJennifer E. Bakker - Drexel UniversityDeborah Nagle - Drexel University
- Publication Details
- Archives of pathology & laboratory medicine (1976), v 127(10), pp 1376-1379
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000185718700025
- Scopus ID
- 2-s2.0-0141995523
- Other Identifier
- 991019168650704721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Medical Laboratory Technology
- Medicine, Research & Experimental
- Pathology