Logo image
Back
Cardiac energy considerations during intraaortic balloon pumping
Journal article   Peer reviewed

Cardiac energy considerations during intraaortic balloon pumping

O Barnea, T.W Moore, S.E Dubin and D Jaron
IEEE transactions on biomedical engineering, v 37(2), pp 170-181
Feb 1990
DOI: https://doi.org/10.1109/10.46257
PMID: 2312142
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Animals Availability Cardiovascular system Computer simulation Heart Medical treatment Myocardium Oxygen Performance analysis Timing
Cardiac oxygen availability and oxygen consumption were used in a theoretical study as indexes of myocardial energy supply and utilization, respectively. A detailed computer simulation of the closed-loop canine cardiovascular system was utilized to study the dependence of these indexes on timing of the intraaortic balloon pump. Oxygen availability exhibited higher sensitivity to balloon timing than oxygen utilization. While maximum augmentation of oxygen availability was 58%, oxygen consumption could be reduced by only 13%. Animal experiments were initiated to validate the theoretical results. The results of both the animal experiments and the computer simulation suggested that neither balloon timing that maximizes oxygen availability nor timing that minimizes oxygen consumption correlates with timing that minimizes aortic end diastolic pressure. Thus, end diastolic pressure, presently used as a determinant of proper timing in patients undergoing cardiac assistance, was found to be a poor index of ventricular energy consumption.< >

Metrics

5 Record Views
30 citations in Web of Science
36 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Web of Science research areas
Engineering, Biomedical
Logo image