Logo image
Back
Cardiac troponin: a critical review of the case for point-of-care testing in the ED
Journal article   Open access   Peer reviewed

Cardiac troponin: a critical review of the case for point-of-care testing in the ED

Roland Bingisser, Charles Cairns, Michael Christ, Pierre Hausfater, Bertil Lindahl, Johannes Mair, Mauro Panteghini, Christopher Price and Per Venge
The American journal of emergency medicine, v 30(8), pp 1639-1649
01 Oct 2012
DOI: https://doi.org/10.1016/j.ajem.2012.03.004
PMID: 22633720
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1016/j.ajem.2012.03.004View
Published, Version of Record (VoR)CC BY-NC-ND V4.0,  Open

Abstract

Emergency Medicine Life Sciences & Biomedicine Science & Technology
The measurement of cardiac troponin concentrations in the blood is a key element in the evaluation of patients with suspected acute coronary syndromes, according to current guidelines, and contributes importantly to the ruling in or ruling out of acute myocardial infarction. The introduction of point-of-care testing for cardiac troponin has the potential to reduce turnaround time for assay results, compared with central laboratory testing, optimizing resource use. Although, in general, many point-of-care cardiac troponin tests are less sensitive than cardiac troponin tests developed for central laboratory-automated analyzers, point-of-care systems have been used successfully within accelerated protocols for the reliable ruling out of acute coronary syndromes, without increasing subsequent readmission rates for this condition. The impact of shortened assay turnaround times with point-of-care technology on length of stay in the emergency department has been limited to date, with most randomized evaluations of this technology having demonstrated little or no reduction in this outcome parameter. Accordingly, the point-of-care approach has not been shown to be cost-effective relative to central laboratory testing. Modeling studies suggest, however, that reengineering overall procedures within the emergency department setting, to take full advantage of reduced therapeutic turnaround time, has the potential to improve the flow of patients through the emergency department, to shorten discharge times, and to reduce cost. To properly evaluate the potential contribution of point-of-care technology in the emergency department, including its costeffectiveness, future evaluations of point-of-care platforms will need to be embedded completely within a local decision-making structure designed for its use. (c) 2012 Elsevier Inc. All rights reserved.

Metrics

9 Record Views
75 citations in Web of Science
82 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Emergency Medicine
Logo image