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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Cardiogenic shock etiology and exit strategy impact survival in patients with Impella 5.5
International journal of artificial organs, v 47(1), pp 8-16
01 Jan 2024
PMID: 38053245
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Despite historical differences in cardiogenic shock (CS) outcomes by etiology, outcomes by CS etiology have yet to be described in patients supported by temporary mechanical circulatory support (MCS) with Impella 5.5.
This study aims to identify differences in survival and post-support destination for these patients in acute myocardial infarction (AMI) and acute decompensated heart failure (ADHF) CS at a high-volume, tertiary, transplant center.
A retrospective review of patients who received Impella 5.5 at our center from November 2020 to June 2022 was conducted.
Sixty-seven patients underwent Impella 5.5 implantation for CS; 23 (34%) for AMI and 44 (66%) for ADHF. AMI patients presented with higher SCAI stage, pre-implant lactate, and rate of prior MCS devices, and fewer days from admission to implantation. Survival was lower for AMI patients at 30 days, 90 days, and discharge. No difference in time to all-cause mortality was found when excluding patients receiving transplant. There was no significant difference in complication rates between groups.
ADHF-CS patients with Impella 5.5 support have a significantly higher rate of survival than patients with AMI-CS. ADHF patients were successfully bridged to heart transplant more often than AMI patients, contributing to increased survival.
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Details
- Title
- Cardiogenic shock etiology and exit strategy impact survival in patients with Impella 5.5
- Creators
- McKenzie Sicke - University of Pittsburgh School of MedicineShan Modi - University of Pittsburgh Medical CenterYeahwa Hong - University of Pittsburgh Medical CenterMichael Bashline - University of Pittsburgh Medical CenterWyatt Klass - University of Pittsburgh Medical CenterEd Horn - University of PittsburghBarinder S Hansra - University of Pittsburgh Medical CenterRaj Ramanan - University of Pittsburgh Medical CenterJeffrey Fowler - University of Pittsburgh Medical CenterNikita Sumzin - University of Pittsburgh Medical CenterRyan M Rivosecchi - University of PittsburghRahul Chaudhary - University of Pittsburgh Medical CenterLuke A Ziegler - University of Pittsburgh Medical CenterNicholas R Hess - University of Pittsburgh Medical CenterNishant Agrawal - University of Pittsburgh School of MedicineDavid J Kaczorowski - University of Pittsburgh Medical CenterGavin W Hickey - University of Pittsburgh Medical Center
- Publication Details
- International journal of artificial organs, v 47(1), pp 8-16
- Publisher
- Sage
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery; Emergency Medicine
- Web of Science ID
- WOS:001114226800001
- Scopus ID
- 2-s2.0-85178929729
- Other Identifier
- 991022008192204721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Transplantation