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Cardiovascular disease risk factor (CVDRF) associated waist circumference patterns in obese-prone children
Journal article

Cardiovascular disease risk factor (CVDRF) associated waist circumference patterns in obese-prone children

Karen L. Leibowitz, Reneé H. Moore, Albert J. Stunkard, Virginia A. Stallings, Robert I. Berkowitz, Nicolas Stettler, Jesse L. Chittams and Myles S. Faith
International journal of pediatric obesity, v 4(3), pp 150-159
01 Jan 2009
PMID: 19101853

Abstract

Objectives. The present study tested whether children born at high risk (HR) compared with low risk (LR) for obesity are more likely to have a waist circumference (WC) associated with cardiovascular disease risk factors (CVDRF-WC) and tested whether CVDRF-WC status tracks over time. Methods. This prospective cohort study involved 71 children, three to eight years, who were divided into two groups, LR (n = 37) and HR (n = 34), based upon maternal prepregnancy body mass index (BMI). HR subjects were subdivided into HR normal-weight (HRNW) and HR overweight (HROW) groups, based on BMI ≥ 85%. Children were classified as having or not having a CVDRF-WC at each year, using age- and gender-specific WC cut-offs. Anthropometry was assessed annually. Results. Although HR children had a significantly greater mean WC than LR children at years 5-8 (p < 0.03), these differences became non-significant after adjusting for BMI. HROW were more likely to have a CVDRF-WC status (p ≤ 0.0001) at age 4 years (10%, 5%, vs. 58%), 5 years (3%, 10%, vs. 60%), 6 years (0%, 0%, vs. 70%), 7 years (0%, 0%, vs. 50%) to 8 years (0%, 0%, vs. 55%) than LR and HRNW. Although 60-100% of the children tracked CVDRF-WC status, higher proportions of HROW children (0-40%) transitioned into having a CVDRF-WC, compared with LR (0-6%) and HRNW (0-9%). Conclusions. HROW were more likely to have or develop a CVDRF-WC. Although the effects of obesity risk on WC may be secondary to BMI, clinically assessing WC in obese-prone children may help identify youth at risk for obesity-related complications.

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Pediatrics
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