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Case Report: Transient Dorsal Midbrain Syndrome as the Initial Presentation of Multiple Sclerosis
Journal article   Peer reviewed

Case Report: Transient Dorsal Midbrain Syndrome as the Initial Presentation of Multiple Sclerosis

Kelly A. Malloy, Erin M. Draper and Ashley Kay Maglione
Optometry and vision science, v 96(8), pp 617-619
01 Aug 2019
DOI: https://doi.org/10.1097/OPX.0000000000001413
PMID: 31318799
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Life Sciences & Biomedicine Ophthalmology Science & Technology
PURPOSE The purpose of this case report is to present a patient with a transient presentation of dorsal midbrain syndrome, resolving within 1 week of initial symptoms, which was ultimately attributed to multiple sclerosis in the setting of a normal enhanced brain MRI study. CASE REPORT A 33-year-old man with new-onset visual complaints was found to have upgaze paresis, eyelid retraction, and pupillary light-near dissociation suggestive of dorsal midbrain syndrome. Within days, enhanced brain MRI was completed and showed a normal finding, and the clinical features of dorsal midbrain syndrome had resolved. Subsequent spine imaging and lumbar puncture lead to an ultimate diagnosis of multiple sclerosis. CONCLUSIONS There have been a few reported cases of dorsal midbrain syndrome as the presenting feature of multiple sclerosis. This case is unique because it reports a transient presentation of dorsal midbrain syndrome, documented to have resolved only days after initial presentation, which was ultimately attributed to multiple sclerosis.

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Web of Science research areas
Ophthalmology
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