Journal article
Case Report of a Woman with Anastrozole-Associated Radiation Recall
Advances in radiation oncology, v 10(1), 101667
Nov 2024
PMID: 39655155
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Radiation recall, an acute reaction localized to previously irradiated areas, can manifest when chemotherapy agents are administered following radiotherapy. Despite being a poorly understood phenomenon, heightened awareness may facilitate early diagnosis and proper management. A diverse range of drugs used in the treatment of cancer has been associated with radiation recall. As most data come from case reports, it is difficult to estimate the true incidence. Radiation recall is inherently drug-specific for each patient, making it challenging to predict individual reactions to specific drugs. Rechallenge attempts do not consistently induce a reaction.
Anastrozole (Arimidex) is an aromatase inhibitor that competitively inhibits the aromatase enzyme, which synthesizes estrogen. It is used for estrogen receptor-positive breast cancers. In this case report, we present a rare occurrence of the radiation recall phenomenon in a breast cancer patient who had completed radiation and subsequently commenced Arimidex treatment.
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Details
- Title
- Case Report of a Woman with Anastrozole-Associated Radiation Recall
- Creators
- Parisa Shamsesfandabadi - Allegheny Health NetworkArpeet Patel - Drexel University, Philadelphia PAVeronica R. Eisen - Allegheny Health NetworkSushil Beriwal - Allegheny Health NetworkColin E. Champ - Allegheny Health Network
- Publication Details
- Advances in radiation oncology, v 10(1), 101667
- Publisher
- Elsevier
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:001368935700001
- Scopus ID
- 2-s2.0-85209990791
- Other Identifier
- 991021944101204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging