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Journal article
Case-control study of tobacco smoke exposure and breast cancer risk in Delaware
BMC cancer, v 8(1), pp 157-157
02 Jun 2008
PMID: 18518960
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background: Tobacco smoke exposure may be associated with increased breast cancer risk, although the evidence supporting the association is inconclusive. We conducted a case-control study in Delaware, incorporating detailed exposure assessment for active and secondhand smoke at home and in the workplace.
Methods: Primary invasive breast cancer cases diagnosed among female Delaware residents, ages 40 -79, in 2000-2002 were identified through the Delaware cancer registry ( n = 287). Delaware drivers license and Health Care Finance Administration records were used to select age frequency-matched controls for women < 65 and >= 65, respectively. Detailed information on tobacco smoke exposure was obtained through telephone interviews.
Results: A statistically significant increased risk of breast cancer was observed for ever having smoked cigarettes ( odds ratio = 1.43, 95% confidence interval = 1.03 - 1.99). However, there was no evidence of a dose-response relationship between breast cancer risk and total years smoked, cigarettes per day, or pack-years. Neither residential nor workplace secondhand smoke exposure was associated with breast cancer. Recalculations of active smoking risks using a purely unexposed reference group of women who were not exposed to active or secondhand smoking did not indicate increased risks of breast cancer.
Conclusion: These findings do not support an association between smoking and breast cancer.
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Details
- Title
- Case-control study of tobacco smoke exposure and breast cancer risk in Delaware
- Creators
- Dana E. Rollison - Moffitt Cancer CenterRoss C. Brownson - Department of Community Health and Prevention Research Center, Saint Louis University School of Public Health, St Louis, USAH. Leroy Hathcock - Delaware Division of Public HealthCraig J. Newschaffer - Drexel University
- Publication Details
- BMC cancer, v 8(1), pp 157-157
- Publisher
- Springer Nature
- Number of pages
- 9
- Grant note
- 2 T32 CA093-14-19 / NCI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) T32CA009314 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- A.J. Drexel Autism Institute
- Web of Science ID
- WOS:000256848100001
- Scopus ID
- 2-s2.0-45449097874
- Other Identifier
- 991019168387304721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Oncology