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Journal article
Case-fatality study of workers and residents with radiographic asbestos disease in Libby, Montana
American journal of industrial medicine, v 65(3)
27 Dec 2021
PMID: 34961951
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background Vermiculite ore from Libby, Montana contains on average 24% of a mixture of toxic and carcinogenic amphibole asbestiform fibers. These comprise primarily winchite (84%), with smaller quantities of richterite (11%) and tremolite (6%), which are together referred to as Libby amphibole (LA). Methods A total of 1883 individuals who were occupationally and/or environmentally exposed to LA and were diagnosed with asbestos-related pleuropulmonary disease (ARPPD) following participation in communitywide screening programs supported by the Agency for Toxic Substances and Disease Registry (ATSDR) and followed up at the Center for Asbestos Related Disease (CARD) between 2000 and 2010. There were 203 deaths of patients with sufficient records and radiographs. Best clinical and radiologic evidence was used to determine the cause of death, which was compared with death certificates. Results Asbestos-related mortality was 55% (n = 112) in this series of 203 patients. Of the 203 deaths, 34 (17%) were from asbestos-related malignancy, 75 (37%) were from parenchymal asbestosis, often with pleural fibrosis, and 3 (1.5%) were from respiratory failure secondary to pleural thickening. Conclusions Asbestos is the leading cause of mortality following both occupational and nonoccupational exposure to LA in those with asbestos-related disease.
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Details
- Title
- Case-fatality study of workers and residents with radiographic asbestos disease in Libby, Montana
- Creators
- Albert Miller - Icahn Sch Med Mt Sinai, New York, NY 10029 USACharles B. Black - Center for Asbestos Related DiseaseGregory Loewen - Washington State University SpokaneCurtis W. Noonan - University of MontanaTracy McNew - Center for Asbestos Related DiseaseAlan C. Whitehouse - Drexel UniversityArthur L. Frank - Drexel University
- Publication Details
- American journal of industrial medicine, v 65(3)
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- 5R01TS000099; P20GM130418 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Center for Asbestos Related Disease Foundation 1 D04RH15013-01 / Health and Human Services HRSA grant Agency for Toxic Substances and Disease Registry-Montana Asbestos Screening and Surveillance Activity (MASSA)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Environmental and Occupational Health
- Web of Science ID
- WOS:000734667000001
- Scopus ID
- 2-s2.0-85121677772
- Other Identifier
- 991019168030104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health