Journal article
Category-specific medial temporal lobe activation and the consolidation of semantic memory: evidence from fMRI
Brain research. Cognitive brain research, v 17(2), pp 484-494
2003
PMID: 12880918
Abstract
Semantic memory consolidation was studied by comparing medial temporal lobe (MTL) fMRI activation to ANIMAL, IMPLEMENT and ABSTRACT nouns in healthy seniors to that of young adults. Relative to healthy seniors, young adults were predicted to show greater MTL activation for IMPLEMENTS, but not ANIMALS, because the ANIMALS category consists of highly intercorrelated and overlapping features that should require less MTL-mediated binding than IMPLEMENTS over a shorter period of time during concept consolidation. ABSTRACT meanings are context-dependent and do not consist of fixed feature sets. Thus it was predicted that ABSTRACT words would not involve age-related feature binding mediated by the MTL. These predictions were confirmed by the results. Our observations are consistent with the hypothesis that the structure of a category influences the consolidation of knowledge in semantic memory.
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Details
- Title
- Category-specific medial temporal lobe activation and the consolidation of semantic memory: evidence from fMRI
- Creators
- John Kounios - Department of Psychology, Drexel University MS626, 245 North 15th Street, Philadelphia, PA 19102-1192, USAPhyllis Koenig - Department of Neurology-2 Gibson, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 18194-4283, USAGuila Glosser - Department of Neurology-2 Gibson, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 18194-4283, USAChris DeVita - Department of Neurology-2 Gibson, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 18194-4283, USAKari Dennis - Department of Neurology-2 Gibson, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 18194-4283, USAPeachie Moore - Department of Neurology-2 Gibson, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 18194-4283, USAMurray Grossman - Department of Neurology-2 Gibson, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 18194-4283, USA
- Publication Details
- Brain research. Cognitive brain research, v 17(2), pp 484-494
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:000186120200028
- Scopus ID
- 2-s2.0-0038443482
- Other Identifier
- 991014877659604721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Computer Science, Artificial Intelligence
- Neuroimaging
- Neurosciences