Files and links (1)
Accepted (AM)Open Access (License Unspecified), Open
Journal article
Cell Membrane Bioconjugation and Membrane-Derived Nanomaterials for Immunotherapy
Bioconjugate chemistry, v 29(3), pp 624-634
01 Mar 2018
PMID: 29323870
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Cell membrane engineering, including live cell membrane bioconjugation and cell membrane-derived nanomaterials is a highly promising strategy to modulate immune responses for treating diseases. Many cell membrane engineering methods have potential for translation for human clinical use in the near future. In this Topical Review, we summarize the cell membrane conjugation strategies that have been investigated for cancer immunotherapy, the prevention of immune rejection to donor cells and tissues, and the induction of antigen-specific tolerance in autoimmune diseases. Additionally, cell membrane-derived or membrane-coated nanomaterials are an emerging class of nanomaterials that is attracting significant attention in the field of nanomedicine. Some of these nanomaterials have been employed to elicit immune responses against cancer, toxins, and bacteria, although their application in establishing immune tolerance has not been explored. In addition to discussing potential problems, we provide our perspectives for promising future directions.
Metrics
Details
- Title
- Cell Membrane Bioconjugation and Membrane-Derived Nanomaterials for Immunotherapy
- Creators
- Peter Y. Li - Drexel UniversityZhiyuan Fan - Drexel UniversityHao Cheng - Drexel University
- Publication Details
- Bioconjugate chemistry, v 29(3), pp 624-634
- Publisher
- American Chemical Society; Washington, DC
- Number of pages
- 11
- Grant note
- R21AI133372 / NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID) R21AI133372 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Materials Science and Engineering
- Web of Science ID
- WOS:000428356300006
- Scopus ID
- 2-s2.0-85044190253
- Other Identifier
- 991019168581604721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biochemical Research Methods
- Biochemistry & Molecular Biology
- Chemistry, Multidisciplinary
- Chemistry, Organic