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Cell-targeted vaccines: implications for adaptive immunity
Journal article   Open access   Peer reviewed

Cell-targeted vaccines: implications for adaptive immunity

Trevor Ung, Nakisha S. Rutledge, Adam M. Weiss, Aaron P. Esser-Kahn and Peter Deak
Frontiers in immunology, v 14, 1221008
01 Aug 2023
url
https://doi.org/10.3389/fimmu.2023.1221008View
Published, Version of Record (VoR)CC BY V4.0 Open

Abstract

adaptive immunity cell targeting innate immunity targeted vaccines vaccine
Recent advancements in immunology and chemistry have facilitated advancements in targeted vaccine technology. Targeting specific cell types, tissue locations, or receptors can allow for modulation of the adaptive immune response to vaccines. This review provides an overview of cellular targets of vaccines, suggests methods of targeting and downstream effects on immune responses, and summarizes general trends in the literature. Understanding the relationships between vaccine targets and subsequent adaptive immune responses is critical for effective vaccine design. This knowledge could facilitate design of more effective, disease-specialized vaccines.

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Collaboration types
Domestic collaboration
Web of Science research areas
Immunology
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