Journal article
Cell‐Free HIV‐1 Virucidal Action by Modified Peptide Triazole Inhibitors of Env gp120
ChemMedChem, v 6(8), pp 1335-1339
01 Aug 2011
PMID: 21714095
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Virus interrupted! Initial entry of HIV‐1 into host cells remains a compelling and yet elusive target for developing agents to prevent infection. Here, we report the ability of modified, site‐ specific peptide triazole inhibitors that target HIV‐1 gp120 to physically disrupt virus particles in the absence of host cells.
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Details
- Title
- Cell‐Free HIV‐1 Virucidal Action by Modified Peptide Triazole Inhibitors of Env gp120
- Creators
- Arangassery R BastianKantharajuKaryn McFaddenCaitlin DuffySrivats RajagopalMark R ContarinoElisabeth PapazoglouIrwin Chaiken
- Publication Details
- ChemMedChem, v 6(8), pp 1335-1339
- Publisher
- WILEY‐VCH Verlag; Weinheim
- Number of pages
- 5
- Grant note
- US National Science Foundation (NSF CBET‐0853680) US National Institutes of Health (NIH‐5 POI GM 56550–13)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology; Computer Science; Thomas R. Kline School of Law
- Web of Science ID
- WOS:000294112900001
- Scopus ID
- 2-s2.0-79960667229
- Other Identifier
- 991014877781204721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Chemistry, Medicinal
- Pharmacology & Pharmacy