Journal article
Cerebral uric acid increases following experimental traumatic brain injury in rat
Brain research, v 733(2), pp 287-291
1996
PMID: 8891312
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Following traumatic brain injury (TBI), cortical and thalamic areas were analyzed histologically and by high-performance liquid chromatography with electrochemical detection for uric acid at various survival times. Following TBI, cortical uric acid was elevated by ten-fold at 24 and 48 h, but not at 1 h post-TBI. Histological evidence of neurodegeneration was found not only in cortex but also in the anteroventral thalamus. These data suggest that as in stroke, uric acid measurements may be a convenient and sensitive method for measuring peroxidative status in TBI.
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Details
- Title
- Cerebral uric acid increases following experimental traumatic brain injury in rat
- Creators
- Emilio C. Tayag - Drexel UniversitySomnath N. Nair - Drexel UniversitySamina Wahhab - Drexel UniversityChristos D. Katsetos - Drexel UniversityJames W. Lighthall - General Motors (United States)John C. Lehmann - Drexel University
- Publication Details
- Brain research, v 733(2), pp 287-291
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:A1996VK40000016
- Scopus ID
- 2-s2.0-0030590439
- Other Identifier
- 991019353622304721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Neurosciences