Journal article
Challenges and Advances in Diagnosis and Treatment of Leptomeningeal Disease (LMD)
Frontiers in oncology, v 11, pp 800053-800053
12 Jan 2022
PMID: 35096602
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Leptomeningeal disease (LMD) is a devastating category of CNS metastasis with a very poor prognosis and limited treatment options. With maximal aggressive therapy, survival times remain short and, without treatment, prognosis is measured in weeks. Both LMD diagnosis and treatment are challenging topics within neuro-oncology. In this review, we discuss the advances in LMD diagnosis with a focus on the role of circulating tumor DNA (ctDNA) and discuss the role of targeted and immunotherapy in LMD treatment.
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Details
- Title
- Challenges and Advances in Diagnosis and Treatment of Leptomeningeal Disease (LMD)
- Creators
- Sherise D. Ferguson - The University of Texas MD Anderson Cancer CenterElena I. Fomchenko - The University of Texas MD Anderson Cancer CenterRenato A. Guerrieri - The University of Texas MD Anderson Cancer CenterIsabella C. Glitza Oliva - College Station Medical Center
- Publication Details
- Frontiers in oncology, v 11, pp 800053-800053
- Publisher
- Frontiers Media Sa
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurology
- Web of Science ID
- WOS:000748012400001
- Scopus ID
- 2-s2.0-85123411609
- Other Identifier
- 991022004954704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Oncology