Logo image
Challenges in large-scale bioinformatics projects
Journal article   Open access   Peer reviewed

Challenges in large-scale bioinformatics projects

Sarah Morrison-Smith, Christina Boucher, Aleksandra Sarcevic, Noelle Noyes, Catherine O'Brien, Nazaret Cuadros and Jaime Ruiz
Humanities & social sciences communications, v 9(1), pp 1-9
08 Apr 2022
url
https://doi.org/10.1057/s41599-022-01141-4View
Published, Version of Record (VoR)CC BY V4.0 Open

Abstract

Arts & Humanities Arts & Humanities - Other Topics Humanities, Multidisciplinary Social Sciences Social Sciences - Other Topics Social Sciences, Interdisciplinary
Biological and biomedical research is increasingly conducted in large, interdisciplinary collaborations to address problems with significant societal impact, such as reducing antibiotic resistance, identifying disease sub-types, and identifying genes that control for drought tolerance in plants. Many of these projects are data driven and involve the collection and analysis of biological data at a large-scale. As a result, life-science projects, which are frequently diverse, large and geographically dispersed, have created unique challenges for collaboration and training. We examine the communication and collaboration challenges in multidisciplinary research through an interview study with 20 life-science researchers. Our results show that both the inclusion of multiple disciplines and differences in work culture influence collaboration in life science. Using these results, we discuss opportunities and implications for designing solutions to better support collaborative tasks and workflows of life scientists. In particular, we show that life science research is increasingly conducted in large, multi-institutional collaborations, and these large groups rely on "mutual respect" and collaboration. However, we found that the interdisciplinary nature of these projects cause technical language barriers and differences in methodology affect trust. We use these findings to guide our recommendations for technology to support life science. We also present recommendations for life science research training programs and note the necessity for incorporating training in project management, multiple language, and discipline culture.

Metrics

15 Record Views
10 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#16 Peace, Justice and Strong Institutions
#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
Web of Science research areas
Humanities, Multidisciplinary
Social Sciences, Interdisciplinary
Logo image