Journal article
Changes in 5-HT and 5-HIAA stores in maturing mouse brain following MAO blockade with pargyline
General pharmacology, v 12(6), pp 493-495
1981
PMID: 6171480
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
1.
1. Levels of 5-hydroxytryptamine (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) were measured in hemispheres and brainstems of maturing mice following monoamine oxidase (MAO) blockade with pargyline.
2.
2. 5-HT elevations were matched by 5-HIAA reduction in 1-, 2- and 6-week-old brains following blockade. 1 Day old brain did not show a 5-HIAA reduction; but did show a 5-HT elevation following blockade.
3.
3. It is suggested that neonatal brain may employ alternative pathway endproducts for 5-HT catabolism.
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Details
- Title
- Changes in 5-HT and 5-HIAA stores in maturing mouse brain following MAO blockade with pargyline
- Creators
- Peter C. Baker - Cleveland State UniversityKenneth M. Hoff - Cleveland State UniversityCecilie A. Goodrich - Cleveland State University
- Publication Details
- General pharmacology, v 12(6), pp 493-495
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biology
- Web of Science ID
- WOS:A1981MR32200015
- Scopus ID
- 2-s2.0-0019786846
- Other Identifier
- 991021463712104721
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- Web of Science research areas
- Pharmacology & Pharmacy