Journal article
Changes in Dietary Magnesium Intake and Risk of Type 2 Diabetes Mellitus in Middle School Students: Using Data from the HEALTHY Study
The Journal of nutrition, v 151(11), pp 3442-3449
02 Nov 2021
PMID: 34313771
Abstract
Background The HEALTHY Study was a multicomponent school-based intervention, designed to prevent type 2 diabetes mellitus (T2DM) in middle-school students. Objectives We examined whether the difference in dietary magnesium intake, BMI percentile, and plasma glucose and insulin concentrations from 6th to 8th grade were related in the intervention schools and in the control schools that participated in the HEALTHY Study. Methods A total of 2181 ethnically diverse students, from 11.3 to 13.7 y of age, with completed dietary records, BMI percentile, and plasma glucose and insulin concentrations at 6th and 8th grades were included. Dietary magnesium intake was self-reported using the Block Kids FFQ. A hierarchical multiple regression model was used to determine whether the differences in dietary magnesium intake, BMI percentile, and plasma glucose and insulin concentrations from 6th to 8th grades were related, while adjusting for dietary calcium intake and total energy intake. Results The difference in dietary magnesium intake was significantly related to changes in BMI percentile from 6th to 8th grade in intervention and in control schools [intervention: beta: -0.07; 95% CI: -0.58, -0.02; P = 0.03; R-2 (regression coefficient effect size): 0.14; 95% CI for R-2: 0.10, 0.17; control: beta: -0.08; 95% CI: -0.63, -0.09; P = 0.01; R-2: 0.12; 95% CI for R-2: 0.08, 0.15]. The difference in dietary magnesium intake was not related to plasma glucose and insulin concentrations in intervention and in control schools. Conclusions We conclude that a multicomponent intervention was associated with reduced risk of T2DM, and that this association may be modulated, in part, by magnesium. The differences in dietary magnesium intake from 6th to 8th grade were negatively related to changes in BMI percentile among middle-school students.
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Details
- Title
- Changes in Dietary Magnesium Intake and Risk of Type 2 Diabetes Mellitus in Middle School Students: Using Data from the HEALTHY Study
- Creators
- Manal Naseeb - King Abdulaziz UniversityMichael L. Bruneau - Drexel UniversityBrandy-Joe Milliron - Drexel UniversityDeeptha Sukumar - Drexel UniversityGary D. Foster - ICF InternationalSinclair A. Smith - Drexel UniversityStella L. Volpe - Virginia Tech
- Publication Details
- The Journal of nutrition, v 151(11), pp 3442-3449
- Publisher
- Oxford Univ Press
- Number of pages
- 8
- Grant note
- National Institute of Diabetes and Digestive and Kidney Diseases of the NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) King Abdulaziz University American Diabetes Association
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]; Nutrition Sciences; Health Sciences
- Web of Science ID
- WOS:000769068300020
- Scopus ID
- 2-s2.0-85119512889
- Other Identifier
- 991019168766904721