Journal article
Characteristics of alkaline phosphatase from two continuous lines of human choriocarcinoma cells
Experimental cell research, v 105(1)
01 Mar 1977
PMID: 837994
Abstract
Several characteristics of human choriocarcinoma alkaline phosphatase have been studied. BeWo and Jar choriocarcinoma lines each contain heat-stable alkaline phosphatase activity with characteristics similar to the D-variant term placental isoenzyme. The activity is also similar to the Nagao enzyme found in many malignancies. Each choriocarcinoma also has heat-labile alkaline phosphatase activity with characteristics similar to the enzyme found in normal first-trimester placenta. Neither BeWo alkaline phosphatase could be stimulated with cortisol. Both BeWo alkaline phosphatase activities could be stimulated with methotrexate and actinomycin D.
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Details
- Title
- Characteristics of alkaline phosphatase from two continuous lines of human choriocarcinoma cells
- Creators
- K.V. Speeg - MRC Laboratory of Molecular BiologyJ.C. Azizkhan - MRC Laboratory of Molecular BiologyK. Stromberg - MRC Laboratory of Molecular Biology
- Publication Details
- Experimental cell research, v 105(1)
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology
- Web of Science ID
- WOS:A1977CY97700021
- Scopus ID
- 2-s2.0-0017332298
- Other Identifier
- 991020200752304721